Dysregulation of another Rab protein, Rab7L1 (Rab29), by mutant LRRK2 has also been linked to PD through dysregulation of E-L trafficking (Simón-Sánchez et al., 2009; MacLeod et al., 2013; Beilina et al., 2014; Kuwahara et al., 2016; Tang, 2017; Liu et al., 2018). This evidence concerns the gene AGFG1 and Parkinson disease.