The pro-inflammatory role of decorin is further underscored by findingsdemonstrating that overexpression of pancreatic decorin is associated withprolonged inflammation in chronic pancreatitis.91 This is due to decorin-dependent overexpression of the chemoattractantCCL2, resulting in enhanced recruitment of mononuclear cells to the injury siteand maintenance of inflammation.91 The gene discussed is DCN; the disease is chronic pancreatitis.