In this series of individuals requiring admission following infection with SARS‐CoV‐2, the possibility presents that possession of the HLA Class I type HLA‐A*26 or the HLA Class II types HLA‐DQB1*06, HLA‐DRB1*15 or HLA‐DRB1*10 results in an impaired ability to present the viral peptides necessary to form a protective T‐cell repertoire. Here, HLA-DRB1 is linked to infection.