The incidences of observed worst grade ≥ 1 AEs were neutropenia (n = 23 patients), increased ALT (n = 15), increased AST (n = 13), hypertension (n = 10), decreased hemoglobin (n = 1), lymphopenia (n = 16), thrombocytopenia (n = 13), and leukopenia (n = 20). This evidence concerns the gene GPT and Decreased total leukocyte count.