Results showed marked increases in mRNA expression of both IL-6 (5-fold, p < 0.001, n = 3) and IL-1β (12-fold, p < 0.001, n = 3) in MCD (NASH) fed mouse group as compared to CHOW diet mouse group (Fig. 2b). The gene discussed is IL6; the disease is metabolic dysfunction-associated steatohepatitis.