Diabetic patients have a great atherosclerotic burden, restenosis after PCI, and more adverse events probably because they are characterized by frequent hyperplasia after PCI, more easily activated platelets, increased levels of fibrinogen, thrombin and coagulation factor VII, proinflammatory states, systemic endothelial dysfunction, and metabolic disorders [21, 34, 35]. This evidence concerns the gene F7 and metabolic disease.