However, in some cases, it has been suggested that LPS can contribute to the severity of Th2 lung inflammation and food allergies (Michel et al., 1996; Rodriguez et al., 2017), which may involve OX40L (Duan et al., 2008) and IFN-I (Pollara et al., 2006). The gene discussed is TNFSF4; the disease is food allergy.