PSMA–Glu–NH–CO–NH–Lys(Ahx)-HBED-CC (PSMA-11) and PSMA–Glu–NH–CO–NH–Lys-2-naphthyl-l-Ala-cyclohexane-DOTA (PSMA-617) are both specific PSMA ligands, which have shown significantly improved binding affinity to PSMA and highly efficient internalization into PCa cells12,13. The gene discussed is FOLH1; the disease is posterior cortical atrophy.