PHGDH and glioblastoma: Univariate Cox regression analysis of our GBM cohort revealed that only 11 of these markers were reproduced at the protein level (Supplementary Data 4), and of those, we identified two biomarkers as favorable for IDH wild-type GBM (phosphoglycerate dehydrogenase, PHGDH, and Raftlin family member 2, RFTN2), and one as unfavorable (FKBP prolyl isomerase 9, FKBP9; Fig. 4c, d).