Recently, Hsu et al. reported that epithelial-mesenchymal transition (EMT) induces N-glycosyltransferase STT3, the catalytically active subunit of OST, and subsequently promotes PD-L1 N-linked glycosylation to stabilize and enrich PD-L1 in cancer stem-like cells, leading to cancer immune evasion [47]. Here, CD274 is linked to cancer.