Immunoglobulin-like transcript (ILT) 4, one of the HLA-G receptors, was found in ccRCC [22] and non-small cell lung cancer in which promotes tumor progression and metastases by increasing the levels of VEGF-C [25], the best characterized and more efficient growth factor involved in lymphangiogenesis and lymphatic metastases [26–28]. Here, VEGFC is linked to neoplasm.