NFKB1 and Neonatal sepsis: For example, microRNA-300 promotes inflammatory responses by targeting nicotinamide phosphoribosyltransferase (NAMPT) and activation of AMPK/mTOR pathway in neonatal sepsis [7]; miRNA-138 accelerates inflammatory responses via binding its target SIRT1 and activating the NF-κB and AKT pathways [8]; in contrast, miR-15a/16 restrains inflammatory responses induced by LPS [9].