CD44 and preeclampsia: Although we did not have longitudinal samples from the same study before and after the clinical onset of preeclampsia, using separate cohorts of pregnant women, we demonstrated that the CD44/FKBPL ratio shows opposite patterns of secretion in plasma postdiagnosis (reflective of restricted angiogenesis) compared to prediagnosis (reflective of stimulated angiogenesis, which could be compensatory at this stage of gestation).