Based on the ROC curve analysis, we were able to determine a suitable cut-off point for the CD44/FKBPL ratio of 143.6 (AUC = 0.659, P = 0.004; sensitivity = 0.7, specificity = 0.51) or 155.1 (sensitivity = 0.6 and specificity = 0.6) for prediction of the risk of preeclampsia at 20 weeks of gestation. Here, FKBPL is linked to preeclampsia.