When CD44 and FKBPL were combined as the CD44/FKBPL ratio, the differences between preeclampsia and control groups demonstrated an increase in the plasma CD44/FKBPL ratio (15th week: 143.1 [113.2-259.2], n = 57, 128.8 [91.2-176.1], n = 56; P = 0.02; 20th week: 181.1 [121.3-302.4], n = 54 vs 143.1 [101.3-176.3], n = 55; P = 0.004, Table 3). This evidence concerns the gene CD44 and preeclampsia.