At 20 weeks of gestation, both CD44 (127.5 ng/mL ± 30.2 SD, n = 62 vs 115.3 ng/mL ± 26.4 SD, n = 60, P = 0.02) and FKBPL plasma concentrations (0.65 [0.44-1.08], n = 57 vs 0.89 [0.61-1.16], n = 58; P = 0.01) were higher and lower in the preeclampsia group compared to controls, respectively. This evidence concerns the gene FKBPL and preeclampsia.