9 out of 10 (PREX1, CAMK2A, DNTTIP1, CRISPLD1, PTGIS, GDF9, FAT2, DOC2B and TCERG1) genes are typically suggested as biomarkers in several cancers and show close correlations with multiple cancer prognoses, including in endometrial cancer, breast cancer (BC), ovarian cancer, lung cancer, oral cancer, and colorectal cancer (CRC) (Dillon & Miller, 2015; Chen et al., 2017; Sawai et al., 2018; Li et al., 2019; Singh, Chandra & Bapat, 2015; Du et al., 2012; Katoh, 2012; Satyamoorthy et al., 2014). This evidence concerns the gene DOC2B and lip and oral cavity carcinoma.