NQO1 and triple-A syndrome: Finally, we correlated AAA size with the level of Nrf2 transcriptional activity, assessed by expression of Nrf2 target gene NQO1. It revealed a positive correlation between aneurysm size and NQO1 level among patients administered with simvastatin (Figure 7(e)—black, Spearman's correlation r = 0.6620, p < 0.001, n = 28).