By autophosphorylation, AKT1 regulates key signaling pathways such as the Janus kinase-signal transducer and activator of transcription (JAK-STAT), apoptosis, mammalian target of rapamycin, and mitogen-activated protein kinase (MAPK) signaling pathways [33, 34], regulates apoptosis and related proteins, thus affecting the process of LF. This evidence concerns the gene WNK2 and Lassa fever.