Among them are the cardiac-related gene GSTM1 (Glutathione S-Transferase Mu 1) (Supplementary Fig. S12A) and genes known to be cardiac relevant like TTR (transthyretin; cardiac amyloidosis and hypertrophic cardiomyopathy) and members of the apolipoprotein family including APOC3 (apolipoprotein C3; apolipoprotein C-III deficiency, Supplementary Fig. S12B,C). The gene discussed is GSTM1; the disease is hypertrophic cardiomyopathy.