In an age-stratified analyses, the impact of perinatal HIV exposure/infection varied with age (≤ 36 months and > 36 months) as HEU children had more similar communities when compared to HUU children in the older group (Figure S3A–B), but CD4% remained significantly associated with diversity distance matrices in both age groups—Figure S3C–D. The gene discussed is CD4; the disease is infection.