In addition to MSLN itself20, several of the 33 genes with higher expression within the MSLN-high group of tumors are associated with poor prognosis and tumor progression in PDAC patients, including KCNN4 (ref.21), TNK2 (ref.22), CAPG23, and MUC1 (ref.24). The gene discussed is KCNN4; the disease is neoplasm.