Here, we assessed for the first time the associations of the total plasma N-glycome with the use of metformin, SU derivatives, insulin, ACE inhibitors/ARB and statins in patients with type 2 diabetes by meta-analyzing the cross-sectional data of two large cohorts, ie, the DiaGene study14 and Hoorn Diabetes Care System (DCS) cohort.15 Here, INS is linked to type 2 diabetes mellitus.