CD36 and nephritis: In addition, CD36 is highly expressed in proximal and distal renal tubular epithelial cells, podocytes, mesangial cells, microvascular endothelial cells and interstitial macrophages, which can mediate the uptake of oxidized LDL (ox-LDL) [32], and also can be combined with various circulating ligands to promote the development of kidney inflammation, oxidative stress and fibrosis [33, 34].