IL15 and B-cell chronic lymphocytic leukemia: The primary outcome of anti-CD19 IL-15 secreted CAR NK cell therapy in patients with B cell lymphoma and CLL indicate that 8 (73%) of the 11 patients with relapsed or refractory CD19-positive cancers achieved a response; of these patients, 7 (4 with lymphoma and 3 with CLL) achieved CR, and 1 achieved remission of the Richter’s transformation component but had persistent CLL.