SPP1 and type 2 diabetes mellitus: Moreover, similar results were proved in the expression levels of SPP1 and ALP, Expression was higher in T2D cells in comparison to the control (SPP1, p = 0.0001; ALP, p < 0.0001) and to cells from patients with insulin resistance (SPP1, p < 0.0001; ALP, p = 0.0263).