AKR1B10 and neoplasm: In the cluster analysis as well, the IHC scores of AKR1B10 and FGF1 were significantly different between tumor and normal tissues (Figure 3G), with 23.9% and 76.1% of the normal samples, and 51.9% and 48.1% tumor samples respectively present in Cluster 1 and Cluster 2 (Figure 3H).