Having demonstrated that Hh/Gli signaling in mouse BCC‐like tumors results in a significant increase in chemokine levels such as Ccl2 and Ccl3—two well‐known chemoattractants for innate immune cells [62, 63]—we next analyzed quantitatively and qualitatively by flow cytometry analysis, whether epidermal Hh pathway activation results in changes of the innate immune cell population. This evidence concerns the gene CCL2 and skin basal cell carcinoma.