GLI1 and skin basal cell carcinoma: In BCC, irreversible activation of HH signaling culminates in high levels of oncogenic GLI transcription factors, which initiate and promote tumor growth by continuous hyperactivation of HH target genes involved in proliferation, survival, angiogenesis, stemness and (de‐) differentiation [2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12].