Having demonstrated that Hh/Gli signaling in mouse BCC‐like tumors results in a significant increase in chemokine levels such as Ccl2 and Ccl3—two well‐known chemoattractants for innate immune cells [62, 63]—we next analyzed quantitatively and qualitatively by flow cytometry analysis, whether epidermal Hh pathway activation results in changes of the innate immune cell population. The gene discussed is GLI1; the disease is skin basal cell carcinoma.