Vaccination of persons with chronic liver disease, including but not limited to personswith hepatitis B virus (HBV) infection, hepatitis C virus (HCV) infection, cirrhosis,fatty liver disease, alcoholic liver disease, autoimmune hepatitis, or an alanineaminotransferase (ALT) or aspartate aminotransferase (AST) level persistently greaterthan twice the upper limit of normal. Here, GPT is linked to autoimmune hepatitis.