Previous mechanistic research has shown that miR-145 could regulate cell proliferation by targeting TGF-β1 in breast cancer (Ding et al., 2017), by targeting NRAS in condyloma acuminatum (Liu et al., 2018), and by regulating ADAM19 in retinoblastoma (Sun et al., 2015). Here, ADAM19 is linked to retinoblastoma.