The WHO classification of hematopoietic tumors from 2008 introduced a provisional entity called large cell B cell lymphoma with features between a DLBCL, NOS and Burkitt lymphoma (BCLU) including large B cell lymphomas with Burkitt-like morphology, but distinct immunohistological features and the frequent presence of C-MYC rearrangements often together with a BCL2 and/or BCL6 rearrangement, so-called double/triple hit (DH) [2, 3]. The gene discussed is BCL6; the disease is diffuse large B-cell lymphoma.