HSPD1 and atherosclerosis: In vitro and in vivo studies have demonstrated that the risk factors to atherosclerosis can cause endothelial disturbances with simultaneous expression of adhesion molecules and HSP60 on the mitochondria, cytoplasm and cells surface, where it can act as dangerous signs to cellular and humoral immune reactions (Wick et al., 2014; Juwono and Martinus, 2016).