Fibulin-1 had a greater area under the receiver operating characteristic curve (AUROC) (0.791; 95% confidence interval (CI): 0.690–0.893) than AFP (0.640; 95% CI: 0.498–0.782), suggesting that Fibulin-1 is superior to AFP at diagnosing HCC (Figure 7B). The gene discussed is AFP; the disease is hepatocellular carcinoma.