TNFSF13B and cancer: BAFF and APRIL have been reported to be trophic factors in lymphocyte malignancies and immune-related disorders (65), while they have been identified in bronchial tissue (66) and a number of immune-related and immune-independent normal and cancer tissues (spleen, liver, lung, heart, intestine, kidney, thymus, breast) (67), although the exact cellular population contributing to their expression was not clearly identified.