Jude children's research hospital have 39 samples, and by WGS,PIK3CA is detected as a mutational cancer driver in the ependymoma cohort in 2 out of 39 (5.13%) samples (3:179203765: T>A; AA345, 3:179221147: A>C, AA726), were found to have mutation in this driver gene41. The gene discussed is PIK3CA; the disease is cancer.