BAP1 and renal cell carcinoma: Another study used the targeted panel designed for hereditary RCC, which includes 19 genes: BAP1, FH, FLCN, MET, MLH1, MSH2, MSH6, MITF, PMS2, EPCAM, PTEN, SDHA, SDHB, SDHC, SDHD, TP53, TSC1, TSC2, and VHL. Pathogenic genetic variants were identified in 6.1% of 1,235 patients with suspected hereditary cancers of various organs, and among the examined cases, 43.7% with available submitted histology were consistent with published literature based on the specific gene alteration.