Epigenome-wide association studies in several cohorts have shown strong associations between DNA methylation at CpG sites in ATP binding cassette subfamily G member 1 (ABCG1) and risk of type 2 diabetes (Hidalgo et al., 2014; Dayeh et al., 2016; Davegardh et al., 2018). The gene discussed is ABCG1; the disease is type 2 diabetes mellitus.