ISLR and gastric cancer: Upon integrated analysis, we observed that high expression of the ISLR gene showed a correlation with low sensitivity to PX-12 (an irreversible inhibitor of thioredoxin-1) (Metcalfe et al., 2016) and NSC632839 (a non-selective isopeptidase inhibitor) (Nicholson et al., 2008), indicating that high ISLR gene expression may be associated with chemoresistance in gastric cancer.