Among these genes, PIGY, PIGW, PIGG, PIGM, PIGV, PIGN, PIGL, PIGA, PIGO, PIGT, PIGC, PIGQ, PIGP, PGAP1, PGAP2, and PGAP3 variants were reported to be related to human genetic diseases (Freeze et al., 2014). The gene discussed is PGAP3; the disease is hereditary disease.