H2BC21 and viral infectious disease: In order to better determine the localization and expression of each protein in the context of the virus infection, Agrobacterium cultures that express the YFP-fused viral proteins were co-infiltrated with Agrobacterium cultures carrying an empty vector (Mock), or TYLCCNV (10A), or TYLCCNV/TYLCCNB (10Aβ) infectious clones into RFP-H2B transgenic N. benthamiana leaves and infiltrated leaves were examined by confocal microscope at 48 and 72 hpi.