When compared with published exhausted CD8+ T cell datasets by gene set enrichment analysis (GSEA), genes upregulated by phenelzine were significantly (p < 0.05) enriched in resolver (34) (HCV) and controller (35) (HIV) infected patients; in naïve compared to early exhausted T cells; CXCR5+ compared to TIM3− T cells (38); latent compared to peak infections (40); memory compared to effector (41); and memory compared to naïve (42) cells (Figure 5B). Here, CXCR5 is linked to infection.