Consistent with our previous results in chemotherapy-resistant CTCs and MDA-MB-231 breast cancer cell lines (21), expression of nuclear LSD1p (nLSD1p) and other mesenchymal markers (SNAI1, CD133) was enriched in TNBC xenografts following treatment with Abraxane (nab-paclitaxel) and doxycycline (Figure 1A, Supplementary Figure 1A). This evidence concerns the gene SNAI1 and breast carcinoma.