First, we confirmed that miR-34a can negatively regulate the expression of GLUT1. Recent studies have shown that inhibition of miR-34a expression can reduce cell death and fibrosis after acute myocardial infarction, and promote the recovery of myocardial function (Boon et al., 2013; Yang et al., 2015). Here, SLC2A1 is linked to acute myocardial infarction.