GCG and cardiomyopathy: In fact, incretins like glucagon-like peptide 1 (GLP-1; produced by enteroendocrine L-cells), and glucose-dependent insulinotropic polypeptide (GIP; produced by enteroendocrine K-cells; Baggio and Drucker, 2007) can regulate appetite, glucose-mediated insulin secretion from pancreatic β-cells (Varndell et al., 1985), and increase GLUT1 expression and translocation to the sarcolemma in cardiomyopathy models (Bhashyam et al., 2010).