Since SCH and ASD have been associated with chronic and low-grade inflammatory states, hence, a considerable number of pro-inflammatory biomarkers, including cytokines such as IL-6, TNF-α, IL-1β, IL-8, IFN-γ, have been identified in both, suggesting the related symptomatic overlap (Cox et al., 2015; Lv et al., 2015; Masi et al., 2015). This evidence concerns the gene IL1B and spindle cell hemangioma.