NDRG1 was found to be the most up-regulated gene in cybrids with cancer cell–derived mitochondria, and it is amplified and up-regulated in a large fraction of patients with the basal subtype of invasive breast carcinoma.17 Silencing NDRG1 significantly reduced proliferation, but has no effect on migration, of SUM-159 cells. This evidence concerns the gene NDRG1 and cancer.