HTRA1 and Miyoshi myopathy: Moreover, the differentially upregulated apoptosis related proteins including Caspase3, Caspase8, Fas, HTRA, and p53 identified by the detection of human apoptosis antibody array (shCHPF vs. shCtrl) suggested the potential involvement of Fas and p53 signaling pathway in the regulation ability of CHPF on MM (Fig. 2c).