Finally, in addition to factors such as age, gender, TNM stage, and tumor stage, we also analyze AFP, HBV, HCV, Alcohol, Family history, Fibrosis Ishak score/Liver cirrhosis, BMI, Platelet result, Performance status, Child-Pugh grade, ALB, Region/Race, Adjacent tissue inflammation, etc. Among them, AFP, HCV, Alcohol, Family history, Fibrosis Ishak score/Liver cirrhosis, BMI, Platelet result, ALB, Region/Race, Adjacent tissue inflammation are not independent factors with significant statistical differences. The gene discussed is AFP; the disease is cirrhosis of liver.