TGFB1 and ovarian cancer: Furthermore, nc886 was shown to interact with DICER and inhibit maturation of many miRNAs, suggesting that nc886 is the factor constituting the previously observed link between TGF-β activation and miRNA suppression in a subtype of ovarian cancer (“integrated mesenchymal” or the “fibrosis” subtype) (Ahn et al. 2018).