EGFR and non-small cell lung carcinoma: Non-small-cell lung cancer (NSCLC) consists of nearly 85% of lung cancer cases (Hou et al. 2019a) and targeted therapeutics based on driver mutations of NSCLC, such as mutations of epidermal growth factor receptor (EGFR) (Santoni-Rugiu et al. 2019) and anaplastic lymphoma kinase (ALK) (Golding et al. 2018), have significantly prolonged the survival of patients.