PBX3 and colorectal carcinoma: Low expression of let-7c-5p is associated with metastasis and cell growth in CRC tissues and up-regulation of let-7c-5p in the highly metastatic Lovo cell line caused a decrease in migration and inhibition of cell growth through targeting matrix metallopeptidase 11 (MMP11) and PBX homeobox 3 gene (PBX3) [40].