NR4A1 and neoplasm: Among the top-ten upregulated DEGs we also found genes involved in cancer, such as FST (a potential marker of HCC), ODC1 and ARAF (both considered associated with tumor promotion), and NR4A1 and NR4A3 (members of the steroid-thyroid-retinoid receptor superfamily of transcription factors, positively regulated by oncogenic signaling pathways).