Myc modulates the metabolism in CRC cells by upregulating anabolic genes involved in fatty acid synthesis (e.g., PTT1), de novo purine (e.g., PRPS2) and pyrimidine (e.g., CAD) synthesis as well as by downregulating catabolic genes like CPT2 engaged in fatty acid oxidation [95]. Here, MYC is linked to colorectal carcinoma.