Then, in 2013, heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) was reported to be involved in ALS after researchers identified three hnRNPA1 variants—two of which were associated with familial ALS and the other of which was associated with a sporadic case [121]. The gene discussed is HNRNPA1; the disease is amyotrophic lateral sclerosis.